The Use of Sodium Salicylate by Intravenous and Intramuscular Administration

نویسنده

  • Suresh Chandra Roy
چکیده

gesic drug" of value in rheumatic and similar affections. But it is almost entirely given by oral administration, and sometimes its use, even in large doses and over prolonged periods, is attended with disappointing results. 1 have used this drug by the intravenous and intramuscular routes for the past twelve years, and have found that this method of administration is far and away superior to administration by the oral route. Further, by such methods of administration the irritable effect which the drug produces on the stomach is avoided. In my experience, on local injection into inflamed and painful joints, etc., it causes local softening, and results in freer and less painful movements of the joints. I have used it in cases of fibrous ankylosis of joints, myalgias, general and localised neuritis, whether severe or chronic; whilst the contra-indications to its intravenous or

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Effects of Peripheral and Intra-hippocampal Administration of Sodium Salicylate on Spatial Learning and Memory of Rats

Objective(s) Cyclooxygenases  (COXs) are known to play some roles in physiological mechanisms related to learning and memory. Since sodium salicylate is an inhibitor of COX, we have evaluated the effect of peripheral and intra-hippocampal administration of sodium salicylate on spatial learning and memory in male rats. Materials and Methods Male rats were studied in two groups; the first grou...

متن کامل

The Enhancing Effect of Sodium Glycocholate and Sodium Salicylate on Rats Gastro-intestinal Permeability to Insulin

There have been numerous efforts to formulate insulin into an oral dosage form. The major problems involved with the oral administration of insulin are acidic and enzymatic decomposition by the gastric medium, and poor absorption in the small intestine due to its macromolecular structure. This study attempted to test the enhancing ability of two absorption enhancers, sodium glycocholate (Na-G...

متن کامل

Pharmacokinetics of ceftriaxone in buffalo calves (Bubalus bubalis) following intravenous and intramuscular administration

Pharmacokinetics of ceftriaxone was studied in buffalo calves (Bubalus bubalis) after single intravenousand intramuscular administration of 10 mg/kg body weight. The drug concentrations in plasma samples weremeasured by high performance liquid chromatography with UV detection. Following intravenousadministration, the drug was rapidly distributed (Cpo: 106.5 ± 9.64 μg/ml; t1/2α: 0.09 ± 0.01 h; V...

متن کامل

Intravenous Injections of Sodium Salicylate

Sir,?For the past two years I have been using the intravenous route for the administration of sodium salicylate in cases of rheumatic and myalgic affections with very good results. The relief of pain is rapid, the stiffness disappears much more quickly than by the oral route of administration; and the period spent in hospital is also cut short. The strength which I use is 10 grains in 10 c.c. o...

متن کامل

Pharmacokinetics of ceftazidime in buffalo calves following intravenous and intramuscular administration

The pharmacokinetic parameters of ceftazidime, a third generation cephalosporin, were investigated in six buffalo calves after single intravenous (IV) and intramuscular (IM) administration at a dose rate of 10 mg/kg body weight. Ceftazidime concentrations in plasma and urine were determined by microbiological assay. Ceftazidime disposition was best fitted by a two-compartmental and a one-compar...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 61  شماره 

صفحات  -

تاریخ انتشار 2017